Reflect on what you learned during this show and earn up to 1 AMA PRA Category 1 Credit ™ (applicable to physicians, nurses, nurse practitioners, PAs): https://earnc.me/n13bR0 For all other health professionals, please check with your state board as to whether they accept these AMA credits for CE requirements. Please note, credit is earned not from the content of the episode, but from your reflection on the content. Powered by CMEfy – a seamless way for busy clinician learners to discover Internet Point-of-Care Learning opportunities that reward CME credits & more. Topics & Timestamps: 00:00 Intro 1:10 A brief history of the Covid vaccines, groups that benefit from boosting 5:12 Incubation periods and vaccination "goals," preventing infection vs. severe disease 10:54 Bivalent vaccine, the FDA's EUA approach, crucial dosing issues (ancestral strain vs. bivalent) 17:15 BA.4/5 booster immunogenicity data (or lack thereof), mouse data & vax safety profile 21:40 Why Paul himself would pass on the new booster, incubation periods, why Covid zero is a fantasy 24:28 Paul's "perfect" bivalent vaccine 25:37 Yearly targeted boosters, myocarditis and the Thai children's study 28:39 BA.4/5: MIS-C, boosters & long Covid, data from JAMA's Italian study 31:28 Comparing BA.4/5 & the yearly flu vax, timing of the yearly flu shot 38:45 Polio's resurgence, injected inactivated vs. live oral polio vaccines, the role of sanitation 48:05 Monkeypox and a history of smallpox vaccines 56:43 Reflection w/Dr. Offit: what he's gotten right, what he's gotten wrong and where to go from here 1:01:57 Final thoughts">
ZDoggMD
Science & Tech • Fitness & Health
A tribe of like-minded folks dedicated to real change in medicine and beyond, and we're healthcare's only unfiltered voice. We represent the Alt-Middle, assuming good intent while engaging in real debate. We refuse to get played by social media's polarizing algorithms, ever.
Interested? Want to learn more about the community?
September 15, 2022
Do We Even Need These Omicron Boosters? (w/Paul Offit)

Our favorite vaccine expert is less than impressed with evidence to support the Omicron BA.4/5 "bivalent" booster shots now rolling out for everyone 12 and older. A must-watch deep dive into some science, here on Locals FIRST!

We also talk polio and monkeypox and flu 👍 Seriously, this interview 🤯

Free for this important episode-->Reflect on what you learned during this show and earn up to 1 AMA PRA Category 1 Credit ™ (applicable to physicians, nurses, nurse practitioners, PAs): https://earnc.me/n13bR0
For all other health professionals, please check with your state board as to whether they accept these AMA credits for CE requirements. Please note, credit is earned not from the content of the episode, but from your reflection on the content. Powered by CMEfy – a seamless way for busy clinician learners to discover Internet Point-of-Care Learning opportunities that reward CME credits & more.

Topics & Timestamps:
00:00 Intro
1:10 A brief history of the Covid vaccines, groups that benefit from boosting
5:12 Incubation periods and vaccination "goals," preventing infection vs. severe disease
10:54 Bivalent vaccine, the FDA's EUA approach, crucial dosing issues (ancestral strain vs. bivalent)
17:15 BA.4/5 booster immunogenicity data (or lack thereof), mouse data & vax safety profile
21:40 Why Paul himself would pass on the new booster, incubation periods, why Covid zero is a fantasy
24:28 Paul's "perfect" bivalent vaccine
25:37 Yearly targeted boosters, myocarditis and the Thai children's study
28:39 BA.4/5: MIS-C, boosters & long Covid, data from JAMA's Italian study
31:28 Comparing BA.4/5 & the yearly flu vax, timing of the yearly flu shot
38:45 Polio's resurgence, injected inactivated vs. live oral polio vaccines, the role of sanitation
48:05 Monkeypox and a history of smallpox vaccines
56:43 Reflection w/Dr. Offit: what he's gotten right, what he's gotten wrong and where to go from here
1:01:57 Final thoughts

01:04:26
Interested? Want to learn more about the community?
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Existential Wknd, pt.2

Axe throwing is SURPRISINGLY therapeutic for that recently discovered repressed anger.

10/10, would recommend.

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Angel’s Landing Zion

Any of y’all hiked this one? FASTEST shortcut to the present moment; gripped that chain so freaking tight, my arms are sore today. Biggest mistake: LOOKING DOWN

Locals video quality is wonky, some cool pics in comments 👇

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July 20, 2025
Your supporter dollars at work 🫣

While immersed in Flushing NY's seriously Chinese vibes, my kids bought a shit-ton of weird-ass snacks and then tried to recreate some random Chinese TikTok video they are obsessed with: https://www.tiktok.com/@gildrtsy/video/7405511542667545861?_r=1&_t=ZP-8y7QlZyNCxz

The result? This 😆

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January 28, 2021
Vaccine Fears, Addressed

Here's last night's live show in podcast form!

Vaccine Fears, Addressed
January 12, 2021
Vaccine Update 1/12/21 w/Dr. Paul Offit

Today's interview with legendary vaccine researcher Paul Offit. Video version coming shortly!

Vaccine Update 1/12/21 w/Dr. Paul Offit
January 01, 2021
New Years Eve Live Show (Flu, Antivax Healthcare Peeps, And More)

Here's an audio podcast version of the last live show of 2020 🥳

New Years Eve Live Show (Flu, Antivax Healthcare Peeps, And More)

How are you all doing today? Schools are closed again tomorrow in Ontario Canada. 40cm...(about 16 inches) of snow fell today and -18C (0F). It's a soup day by the fire. Watching CNN and the ice storms down your way seem worse. Everyone ok?

Amazing story. I can relate to this Columbian woman's NDE and OBE experiences but I'm sharing this mainly for her wondeful descriptions of her momentary awakenings and transpersonal observations.

January 24, 2026

First time watching Interstellar on a BIG screen for both me and the boy! So good we forgot to eat our popcorn! We (he) decided before Christmas that instead of a Christmas play this year (it was Snow White) we'd book this for January - I was a bit sad but actually - growing up is good isn't it! Just a whole load more things to share.

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