Our favorite vaccine expert is less than impressed with evidence to support the Omicron BA.4/5 "bivalent" booster shots now rolling out for everyone 12 and older. A must-watch deep dive into some science, here on Locals FIRST!
We also talk polio and monkeypox and flu 👍 Seriously, this interview 🤯
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Topics & Timestamps:
00:00 Intro
1:10 A brief history of the Covid vaccines, groups that benefit from boosting
5:12 Incubation periods and vaccination "goals," preventing infection vs. severe disease
10:54 Bivalent vaccine, the FDA's EUA approach, crucial dosing issues (ancestral strain vs. bivalent)
17:15 BA.4/5 booster immunogenicity data (or lack thereof), mouse data & vax safety profile
21:40 Why Paul himself would pass on the new booster, incubation periods, why Covid zero is a fantasy
24:28 Paul's "perfect" bivalent vaccine
25:37 Yearly targeted boosters, myocarditis and the Thai children's study
28:39 BA.4/5: MIS-C, boosters & long Covid, data from JAMA's Italian study
31:28 Comparing BA.4/5 & the yearly flu vax, timing of the yearly flu shot
38:45 Polio's resurgence, injected inactivated vs. live oral polio vaccines, the role of sanitation
48:05 Monkeypox and a history of smallpox vaccines
56:43 Reflection w/Dr. Offit: what he's gotten right, what he's gotten wrong and where to go from here
1:01:57 Final thoughts
Fun captioned vertical version of our recent YouTube Live conversation, with no ads, here for Locals fam!
Axe throwing is SURPRISINGLY therapeutic for that recently discovered repressed anger.
10/10, would recommend.
Today's interview with legendary vaccine researcher Paul Offit. Video version coming shortly!
In the recent live someone mentioned the different sleep patterns we've had in the past. It was one of those strange coincidences to me as I'd recently learnt that visiting Little Moreton Hall in England. Built in 1504 and decorated in the great hall with this plaster work celebrating a book written by Robert Recorde (he invented the Equals sign). The book was about the split in human thinking, reasoning, belief...science and magical thinking. Nothing's really changed has it and I'm still wondering what they did when they got up in the middle of a dark, cold night with no electricity to do some chores.
